Abstract:

OBJECTIVE: To summarize the research process of adhesion prevention during tendon rupture repair, to emphasize the injury type of tendon rupture, and to investigate anti-adhesion membranes for preventing tendon adhesions.
METHODS: Using “tendon rupture, tendon adhesion, anti-adhesion membrane” as the Chinese key words, “tendon adhesion, absorbability antiseize continually membrane, anti-adhesion membrane” as the English key words, a computer search of China Academic Journal Full-text database and PubMed database between January 1993 and March 2010 was performed. Articles related with the repair of tendon rupture, prevention of tendon adhesion, biofilm were included; repeated study or Meta analysis articles were excluded. Eighteen studies focused mainly on the type and performance of anti-adhesion membrane for the repair of exercise-induced tendon rupture.
RESULTS: Totally 94 literatures were primary screened out. According to inclusion and exclusion criteria, the prevention mechanism and action theory of drug film, absorbable anti-adhesion membrane, autologous and allogeneic anti-adhesion membrane, non-biological anti-adhesion membrane on the tendon adhesion resulted from tendon injury, were analyzed. Anti-adhesion membrane has always been an issue concerned the medical profession. Anti-adhesion membrane can promote endogenous healing and avoid exogenous healing. There is a wide range of anti-adhesion membrane, its composition and nature may be varied, as well as different performances of anti-adhesion.
CONCLUSION: The anti-adhesion membrane prevents or reduces the adhesion through barrier function of the film, drug films could reduce the adhesion by affecting tendon endogenous and exogenous healing (mainly endogenous healing), through the pharmacological effects. Absorbable membrane may be absorbed by the body and be excreted from the body, without toxicity or adverse reactions.